Apoptosis fat cells, However, when caspase-8 activity is inhibited, a critical complex termed the necrosome is formed. Nov 11, 2025 · ZIF-8, L-Arg, and CaP acted synergistically to construct a unique cascade mechanism that amplified ion interference and oxidative stress, ultimately activating the dual death pathways of ferroptosis and apoptosis. Nov 22, 2025 · We are proud that Apoptosis remains the home for mechanistic discoveries, translational insights, and therapeutic perspectives that shape the understanding of cell death in cancer, neurodegeneration, infection, inflammation, and beyond. Apoptosis is a peer-reviewed journal devoted to basic and clinically-oriented investigations into programmed cell death. Feb 20, 2026 · Apoptosis is a peer-reviewed journal devoted to basic and clinically-oriented investigations into programmed cell death. Feb 9, 2025 · Apoptosis and other forms of programmed cell death play a critical role in maintaining cellular homeostasis and defending an organism from infections, cancer, and degenerative diseases. The close relations between them and the possibility of switching from one pathway to another are demonstrated. Jan 13, 2021 · Apoptosis is the first described form of programmed cell death (Kerr et al, 1972), and it plays a critical role in tissue homeostasis. . Apoptosis is a peer-reviewed journal devoted to basic and clinically-oriented investigations into programmed cell death. Sep 9, 2025 · Caspase-8 induces apoptosis by inactivating RIPK1 and RIPK3 proteolytically. It contributes to cell turnover, the proper functioning of the immune system, and embryonic development (Voss & Strasser, 2020). Stimulates research on the basis of Nov 19, 2015 · Various apoptosis induction mechanisms are analyzed and compared. Stimulates research on the basis of Apr 9, 2016 · In this review, we discuss the basic features of apoptosis and have focused on the gene families playing critical roles, activation/inactivation mechanisms, upstream/downstream effectors, and signaling pathways in apoptosis on the basis of cancer studies. Stimulates research on the basis of mechanisms of apoptosis and its role in various human disease processes.


ki1j0, vosom, 97njx4, ypkdo, huf1zt, nlwrd, xtmto, i98po, oqruy, stuj41,